PDG5 Changes in Canadian Guidelines for Conducting Budget IMPACT Analysis

نویسندگان

چکیده

While the Patented Medicine Prices Review Board (PMPRB) 2007 Budget Impact Analysis (BIA) Guidelines were once considered to be a primary resource for preparation of pharmaceutical BIAs, they no longer reflect current best practices. Recently, thorough review and revision BIA was undertaken by PMPRB staff more closely align them with Canadian requirements international approaches. With new streamlined Excel model template released this year, presentation will outline major changes explain reasoning behind updates. To inform changes, undertook systematic national guidelines practices in collaboration Cornerstone Research Group. In addition, regulatory public funding reviewers surveyed gather input on main issues addressed: gaps challenges former Guidelines, time horizon, non-drug condition-related costs, comparators, multiple indications. The updates involve added flexibility selecting horizon recommendations target population assessment, consideration compliance persistence cost treatments, evolving indications, off-label comparators. Other modifications include model, updated methods used uncertainty analysis, relevant resulting enhanced methodology, as well increased transparency consistency afforded these revised ensure that continue reliable comprehensive reference conducting BIAs Canada.

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ژورنال

عنوان ژورنال: Value in Health

سال: 2021

ISSN: ['1098-3015', '1524-4733']

DOI: https://doi.org/10.1016/j.jval.2021.04.453